Web7. aug 2014 · TOP2A gene is coamplified with HER2 gene in approximately 35% of HER2-amplified breast cancers, and TOP2A coamplification, not HER2 amplification, is the predictive marker of an incremental response to anthracycline-based chemotherapy in HER2-amplified breast cancers [7, 20–23]. Webtop2a 在蛋白质合成与 dna 复制中会剪切双链 dna 螺旋。 该酶过表达会诱导肿瘤发生和进展(Pei et al. 2024)。 TOP2A 过表达与肿瘤转移及患者生存期短相关,因此,TOP2A 被视 …
TOP2A as marker of response to pegylated lyposomal doxorubicin …
Web11. jan 2024 · Neutrophils are the most abundant innate immune cells in the circulation and they are the first cells recruited to sites of infection or inflammation. Almost half of the intracellular protein content in neutrophils consists of S100A8 and S100A9, though there has been controversy about their actual l … WebTOP2A. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. chalon hebrew meaning
TOPBP1 recruits TOP2A to ultra-fine anaphase bridges to aid in
WebThis is a list of gene expression markers are used to define cell types. Green rows indicate canonical markers (classical markers used to define the cell type). Summary: 8286 … Web18. máj 2024 · M1和M2型注释:M1(FCGR3A)和M2(CD163)通常很难区分,一般会表达两种状态的marker gene。文献中提供的注释方法是计算M1和M2极化和抗炎促炎分 … DNA topoisomerase IIα is a human enzyme encoded by the TOP2A gene. Topoisomerase IIα relieves topological DNA stress during transcription, condenses chromosomes, and separates chromatids. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another. Two forms of this enzyme exist as likely products o… happy national butter day