WebApr 8, 2024 · The input for SCENIC is a single-cell RNA-seq expression matrix (with gene-symbol as `rownames`, see the `vignette ("SCENIC_Setup")` for details). The first step is to … WebNov 6, 2024 · By computational analysis of the recently published mouse cell atlas data, we have identified 202 regulons whose activities are highly variable across different cell types, and more importantly, predicted a small set of essential regulators for each major cell type in mouse. Systematic validation by automated literature and data mining provides ...
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WebOct 9, 2024 · SCENIC was run independently for each of the three data sets used for the GRN comparison: Zeisel et al. 9 (mouse brain cells), Lake et al. 11 (human neurons nuclei) and … WebMay 18, 2024 · SCENIC对细胞数量的扩展性不够好。(太多细胞会降低SCENIC的性能) 测序深度不够会影响SCENIC的结果。(Micorwell-seq的测序深度相对于其它技术较浅) 作者随后在figure S1中说明了Avg20的对聚类效果的提升以及对regulon的稳定性的影响。 WebMouse (mgi) Fly (flybase) Chicken ; For each specie, we provide annotations depending on the motif collection used: v8 (only Drosophila): Annotations based on the 2016 cisTarget … baskin robbins juan tabo