WebHuman Phospho-STAT5a/b (Y694/Y699) Antibody Summary Species Reactivity Human Specificity Detects human STAT5a/b when phosphorylated at Y964/Y699 in direct ELISAs and Western blots. Source Recombinant Monoclonal Rabbit IgG Clone # 1247C Purification Protein A or G purified from cell culture supernatant Immunogen WebSTAT5 alpha is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.
Phospho-STAT5 (Tyr694) Monoclonal Antibody (SRBCZX), FITC …
WebOncostatin M (OSM) and leukemia inhibitory factor (LIF) signaling protects the heart after myocardial infarction (MI). In mice, oncostatin M receptor (OSMR) and leukemia inhibitory factor receptor (LIFR) are selectively activated by the respective cognate ligands while OSM activates both the OSMR and LIFR in humans, which prevents efficient translation of … WebSee all STAT5 primary antibodies Description Rabbit monoclonal [E208] to STAT5 (phospho Y694) Host species Rabbit Tested applications Suitable for: WB, IHC-P, ELISA more … diabetes statistics in georgia
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WebPhosphorylated STAT5 (pSTAT5) translocates into the nucleus to regulate transcription of the target genes including the IL-2 receptor α (IL-2Rα) (CD25) ( Figure 1) ( 5, 12 – 14 ), a prerequisite for the formation of the … WebDescription. STAT5 is a member of the signal transducer and activator of transcription factors (STAT) family, mediating growth and cytokine signaling. STAT5 consists of two … WebMar 21, 2024 · The expression of STAT5 was thus the only noted difference in signaling proteins between HMC-1.2 and HMC-1.3 cells. However, the ratio of phospho-STAT5 to total STAT5 was similar in both cell lines with D816V (alone or in combination with V560G) (Figure 2C). Cells with gain-of function in KIT are known to appear refractory to SCF . diabetes statistics in australia 2022