Phospho btk antibody
WebHuman Phospho-BTK (Y223) Antibody R&D Systems, Inc. a Bio-Techne Brand Catalog # MAB7205 (2) Product Datasheet / COA / SDS (2) Catalog # Availability Size / Price Qty MAB9356-SP Contact Us For Delivery Time 25 ug / $123.00 MAB9356-100 In Stock 100 ug / $438.00 Add To Cart Print Quote Bulk Order Key Product Details Order Information WebSpecificity: Phospho-BTK (Tyr223/Tyr225) Antibody detects endogenous levels of BTK only when phosphorylated at Tyr223/225. RRID: AB_2843794. Cite Format: Affinity Biosciences Cat# AF7354, RRID:AB_2843794. Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non ...
Phospho btk antibody
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WebSep 21, 2024 · Bruton tyrosine kinase (BTK) is a TEC family cytoplasmic tyrosine kinase essential for B cell activation mediated through the B cell receptor 3. Other nonreceptor TEC family kinase (TFK) members... WebPolyclonal Antibody for studying BTK (Tyr223) phosphate. Cited in 64 publications. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, Phospho-Btk (Tyr223) Antibody (CST #5082) is ready to ship.
WebUniProt Protein Function: Btk: a tyrosine kinase of the Tec family. Plays a crucial role in B-cell ontogeny. Defects cause X-linked agammaglobulinemia, an immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement. WebBruton’s tyrosine kinase (BTK) is a Tec family kinase that plays a critical role in B cell development. Upon B cell receptor engagement, BTK translocates to the plasma membrane, where it is transphosphorylated by LYN and SYK kinases at Tyr 551. This initial phosphorylation event is followed by autophosphorylation at Tyr 223.
WebThe membrane-localized Btk is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinases, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation (6,7). WebSep 23, 2024 · BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity In Special Collection: The Inflammasomes: From Mechanism to Therapeutics Zsófia Agnes Bittner , Xiao Liu , Maria Mateo Tortola , Ana Tapia-Abellán , Sangeetha Shankar , Liudmila Andreeva , Matthew Mangan , Marianne Spalinger , Hubert Kalbacher , Peter …
WebBTK [p Tyr223] Antibody (EP420Y) Summary. A phospho specific peptide corresponding to residues surrounding tyrosine 223 of human BTK was used as an immunogen. This antibody detects BTK phosphorylated on tyrosine 223. Test in a species/application not listed above to receive a full credit towards a future purchase.
WebAnti-BTK (phospho Y223) antibody See all BTK primary antibodies Description Rabbit polyclonal to BTK (phospho Y223) Host species Rabbit Tested applications Suitable for: … solar energy wallpaperWebApplication Notes. Clones A16128C and A16128B (anti-BTK Phospho (Tyr223)) both bind BTK Phospho Tyr223 with similar affinity, but in comparison to clone A16128B, clone A16128C has a much stronger recognition of phosphorylated Tyrosine 180 of ITK by intracellular staining and flow cytometric analysis. ITK is the T cell-specific homolog of … solar energy to thermal energyWebOct 3, 2012 · Anti-BTK (phospho Y551) antibody See all BTK primary antibodies Description Rabbit polyclonal to BTK (phospho Y551) Host species Rabbit Tested applications Suitable for: WB more details Species reactivity Reacts with: Human Immunogen Synthetic peptide corresponding to Human BTK aa 500-600 (phospho Y551). Database link: Q06187 … solar energy to power a housesolar energy vocational schoolsWebThe antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns. Storage: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt. Alias: Fold/Unfold solar energy vs electricityWebAnti-BTK (phospho Y551) antibody [EP267Y] - BSA and Azide free See all BTK primary antibodies Description Rabbit monoclonal [EP267Y] to BTK (phospho Y551) - BSA and Azide free Host species Rabbit Specificity Stimulation may be required to allow detection of the phosphorylated protein. solar energy wave hits earthWebPhospho-TTK (Thr676) Polyclonal Antibody detects endogenous levels of TTK only when phosphorylated at Thr676. Target Information This gene encodes a constant regulatory … solar energy to invest in