Dynamic phototuning of 3d hydrogel stiffness
WebThe paper, Dynamic Phototuning of Hydrogel Stiffness, describes a technique using a 3D hydrogel cell culture system where the stiffness of the extracellular matrix, the outside perimeter of a cell, can be adjusted with light. Changes in stiffness are observed in cancer, cardiovascular disease, wound healing, and are likely involved in disease ... WebDynamic phototuning of 3D hydrogel stiffness [Applied Biological Sciences] Hydrogels are widely used as in vitro culture models to mimic 3D cellular microenvironments. The …
Dynamic phototuning of 3d hydrogel stiffness
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WebSep 5, 2024 · Hydrogel stiffness was determined by calculating Young's modulus from frequency sweep measurements obtained from a rheometer (B). Figure 2. MDA-MB-231 cells have a stiffness-dependent resistance to doxorubicin. ... Suggs L. Dynamic phototuning of 3D hydrogel stiffness. Proc Natl Acad Sci USA. (2015) 112:1953–8. … WebApr 1, 2024 · Dynamic phototuning of 3D hydrogel stiffness. Proc. Natl. Acad. Sci. U. S. A. (2015) J. Yoon Local switching of chemical patterns through light-triggered unfolding of creased hydrogel surfaces. Angew Chem. Int. Ed. Engl. (2012) T. Miyata et al. A reversibly antigen-responsive hydrogel.
WebFeb 17, 2015 · Temporal modulation of hydrogel stiffness is a powerful tool that will enable investigation of the role that dynamic microenvironments play in biological processes … WebSep 25, 2024 · The development of a hydrogel that incorporates photoswitchable cross-linkers, which can reversibly alter their stiffness upon irradiation with the appropriate …
WebHow- ever, no cell culture systems exist to appropriately model temporal changes in ECM stiffness to determine the biological relevance and mechanisms involved. Here, we … WebAug 15, 2024 · The hydrogel with dynamic increased stiffness was prepared with methacrylated gelatin (GelMA)/sodium alginate (SA) containing CaCO 3 and D-(+) …
WebSep 27, 2024 · Hence, in this study we investigated both the temporal and spatial variations in the stiffness of 3D cell culture systems using a laser speckle contrast shear wave imaging system with a total ...
WebFeb 2, 2015 · Here, we present a 3D hydrogel cell culture system in which the matrix stiffness can be tuned by light. Our approach offers both spatial and temporal control of … how do i prove i am fully covid vaccinatedWebTo recapitulate dynamic microenvironments, a hydrogel with temporally tunable stiffness is needed. Here, we present a system in which alginate gel stiffness can be temporally … how do i protect myself from emfWebAug 24, 2024 · Furthermore, on-demand control of the hydrogel stiffness was achieved by an on-demand stimulus of heating. ... “Dynamic phototuning of 3D hydrogel stiffness,” Proceedings of the National … how much money does a newborn costWebMay 30, 2024 · Here, we utilize a dynamic 3D hydrogel capable of dynamic stiffening to interrogate the role of matrix stiffening on the invasive transformation of mammary epithelial cells. ... Dynamic phototuning of 3D hydrogel stiffness. PNAS. 2015; 2: 201421897. Google Scholar. OpenURL Placeholder Text how do i prove i am cherokee indianWebThe low stiffness of the hydrogels combined with the user-defined adaptability of soft DNA interactions can be particularly suited to address cellular response in 3D matrices, for example, using cell culture grown as spheroids. 16 The thermosensitive response of the PIC polymers 6 induces polymer bundling resulting in hydrogels with higher ... how much money does a nuke costWebHere, we present a 3D hydrogel cell culture system in which the matrix stiffness can be tuned by light. Our approach offers both spatial and temporal control of stiffness, is … how do i prove insolvency to the irsWebAug 1, 2024 · Dynamic phototuning of 3D hydrogel stiffness. Article. Feb 2015; Ryan Stowers; Shane C. Allen; Laura J. Suggs; Hydrogels are widely used as in vitro culture models to mimic 3D cellular ... how do i prove i am the executor of an estate