Consomic strain
WebA congenic strain is derived by mating mice carrying a foreign gene of interest in each succeeding generation to mice of an inbred strain. A fully congenic strain and the inbred … WebFeb 11, 2015 · Using experimental allergic encephalomyelitis (EAE), a mouse model of MS, we evaluated genetic control of disease course among a panel of 26 consomic strains of mice inheriting chromosomes from the wild-derived PWD strain on the C57BL/6J background, which models the genetic diversity seen in human populations.
Consomic strain
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WebOct 19, 2024 · Utilizing a panel of 27 B6.Chr PWD consomic mice, we identified strain-specific microbiota profiles and complex relationships between host genetics, microbial constituents, and microbial-driven metabolic functions associated with differential susceptibility to EAE. In parallel, using a reductionist approach focusing on two of the … WebPubMed Central (PMC)
http://www.rgd.mcw.edu/nomen/rules-for-nomen.shtml WebConsomic strains, also known as chromosome substitution strains, are powerful tools for assigning polygenes that control quantitative complex traits to specific …
WebMar 1, 2003 · Like the consomic strains, these congenic strains also represent a renewable resource. The use of congenic strains has been very limited until this time because development of a congenic line typically requires 10–12 generations of backcrossing, after completion of the crossbreeding studies to define the QTL of interest. ... WebNov 24, 2024 · These strains allow reproducible and efficient whole-chromosome mapping (Flint and Eskin, 2012 ). In contrast, consomic strains, also termed chromosome substitution strains, possess a substitution of one whole chromosome pair from the donor strain into the genetic background of the host strain.
WebConsomic strains are special type of congenic strains. The differential segment between the consomic strain and its parental (progenitor) strain is represented by a whole chromosome. Consomic strains are often used …
http://informatics.jax.org/silver/chapters/3-3.shtml chimney sweeper rhode islandWebAn inbred strain that contains a single entire chromosome from another strain. Consomic (or Chromosome Substitution Strains) are derived by backcrossing to a parental inbred … graduation verification form uscWebConsomic inbred strains are also created through successive backcrossing to a different inbred strain, but the choice of breeders is based on an entire chromosome, not just one … graduation wall artWebMar 1, 2003 · In the case of a consomic (chromosome-substitution) strain, a whole chromosome is transferred 15,16, whereas in the case of a congenic strain, a defined chromosomal segment, the differential ... graduation university of oregonWebany consomic strain within 6 months, by an F2 intercross of the consomic with the background parental strain. These rats are likely to become a national resource for rat research. The website, which currently gets 2,000 visits per month (figure 3), enables investigators to download data or to use the analytical chimney sweepers near me in spooner wiWebStrain State: Strain Type: Any closed colony coisogenic strain congenic strain consomic or chromosome substitution strain hybrid inbred strain major histocompatibility congenic minor histocompatibility congenic mutant stock mutant strain noninbred stock outbred stock recombinant congenic recombinant inbred segregating inbred unclassified wild ... chimney sweepers act 1788WebFeb 11, 2016 · Of the 23 genes within the narrowed congenic interval, 12 were differentially expressed between the resistance vasculature of the 2 … graduation university of bath